Vaccine Spike vs. SARS-COV-2 Spike

Vaccine Spike vs. SARS-COV-2 Spike

Vaccine Spike vs. SARS-COV-2 Spike

There has been a lot of discussion for the spike and ACE2 binding. I have recorded many talks on this topic as well. However, an important piece missing for us has been to understand the difference of the spike between the vaccine and the virus. Let’s review these differences.

If you like this content and want more, I am doing a special one-time membership offer. Click here: https://www.drbeen.com/yt-special/

Want to support this work?:
Buy me a coffee 🙂 https://www.buymeacoffee.com/DrMobeenSyed
Become my patron: https://www.patreon.com/mobeensyed?fan_landing=true
PayPal: https://paypal.me/mobeensyed?locale.x=en_US
My substack: https://mobeensyedmd.substack.com/

#drbeen #koolbeens #COVID

Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

URL list from Thursday, Nov. 17 2022

DrBeen: Medical Education Online

Home

SARS-CoV-2 spike protein: pathogenesis, vaccines, and potential therapies | SpringerLink
https://link.springer.com/article/10.1007/s15010-021-01677-8

SARS-CoV-2 structural features may explain limited neutralizing-antibody responses | npj Vaccines
https://www.nature.com/articles/s41541-020-00264-6

SARS-CoV-2 spike behavior in situ: a Cryo-EM images for a better understanding of the COVID-19 pandemic | Signal Transduction and Targeted Therapy
https://www.nature.com/articles/s41392-020-00365-7

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen | PNAS
https://www.pnas.org/doi/10.1073/pnas.1707304114

An mRNA Vaccine against SARS-CoV-2 — Preliminary Report | NEJM
https://www.nejm.org/doi/full/10.1056/NEJMoa2022483

Structure-based design of prefusion-stabilized SARS-CoV-2 spikes – PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402631/

SARS-CoV-2 prefusion spike protein stabilized by six rather than two prolines is more potent for inducing antibodies that neutralize viral variants of concern | PNAS
https://www.pnas.org/doi/full/10.1073/pnas.2110105119

Frontiers | Enhancing the Prefusion Conformational Stability of SARS-CoV-2 Spike Protein Through Structure-Guided Design
https://www.frontiersin.org/articles/10.3389/fimmu.2021.660198/full

Closing coronavirus spike glycoproteins by structure-guided design – PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302216/

Prefusion Coronavirus Spike Proteins and Their Use | Technology Transfer
https://www.techtransfer.nih.gov/bundle/tab-3261

Locking Down Shape-Shifting Spike Protein Aids Development of COVID-19 Vaccine – UT News
https://news.utexas.edu/2020/08/05/locking-down-shape-shifting-spike-protein-aids-development-of-covid-19-vaccine/

SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets | eLife
https://elifesciences.org/articles/63646

Epitope – Wikipedia
https://en.wikipedia.org/wiki/Epitope

SARS-CoV-2カテゴリの最新記事

pocketlinehatebuimagegalleryaudiovideocategorytagchatquotegoogleplusfacebookinstagramtwitterrsssearchenvelopeheartstaruserclosesearch-plushomeclockupdateeditshare-squarechevron-leftchevron-rightleafexclamation-trianglecalendarcommentthumb-tacklinknaviconasideangle-double-upangle-double-downangle-upangle-downstar-halfstatus