Revealed – How SARS-COV-2 Escapes Our Immune System
This thorough study reveals the mechanism of immune escape by SARS-COV-2. Let’s review.
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Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
URL list from Tuesday, Aug. 2 2022
SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis | Nature Communications
https://www.nature.com/articles/s41467-021-26910-8
NLRC5: a newly discovered MHC class I transactivator (CITA) – PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323719/
CD45 functions as a signaling gatekeeper in T cells | Science Signaling
https://www.science.org/doi/10.1126/scisignal.aaw8151#:~:text=CD45%20is%20a%20receptor%2Dtype,to%20phosphorylate%20the%20TCR%20complex.
Transactivation – Wikipedia
https://en.wikipedia.org/wiki/Transactivation
Promoter
https://www.genome.gov/genetics-glossary/Promoter
Epigenetic Regulation and Measurement of Epigenetic Changes – PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839622/#:~:text=Epigenetic%20regulation%20increases%20the%20functional%20complexity%20of%20DNA%20by%20providing,epigenetic%20modulation%20of%20gene%20expression.
T Cells and MHC Proteins – Molecular Biology of the Cell – NCBI Bookshelf
https://www.ncbi.nlm.nih.gov/books/NBK26926/#:~:text=Class%20I%20MHC%20proteins%20are,microbe%20such%20as%20a%20virus.
Transcription factor – Wikipedia
https://en.wikipedia.org/wiki/Transcription_factor
Interferon gamma – Wikipedia
https://en.wikipedia.org/wiki/Interferon_gamma
Interferon-γ signaling. Canonical IFN-γ signaling pathway requires… | Download Scientific Diagram
https://www.researchgate.net/figure/Interferon-g-signaling-Canonical-IFN-g-signaling-pathway-requires-activation-of-its_fig1_345005034
Interferon regulatory factor 1 (IRF1) and anti-pathogen innate immune responses – PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7819612/
