Roger Seheult, MD of MedCram examines vilobelimab in the treatment of severe COVID with possible applications in the treatment of other diseases. See all Dr. Seheult’s videos at: https://www.medcram.com
(This video was recorded on May 7th, 2023)
Roger Seheult, MD is the co-founder and lead professor at https://www.medcram.com
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.
LINKS / REFERENCES:
Controlling the anaphylatoxin C5a in diseases requires a specifically targeted inhibition (Clinical Immunology) | https://www.sciencedirect.com/science/article/abs/pii/S1521661617301729?via%3Dihub
The anti-C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID-19 (Clinical and translational science) | https://pubmed.ncbi.nlm.nih.gov/35029045/
Anti-C5a antibody (vilobelimab) therapy for critically ill, invasively mechanically ventilated patients with COVID-19 (PANAMO): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial (Lancet Respir Med) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9451499/pdf/main.pdf
Treatment With Anti-C5a Antibody Improves the Outcome of H7N9 Virus Infection in African Green Monkeys (Clinical infectious diseases) | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112341/
FACT SHEET FOR HEALTHCARE PROVIDERS: EMERGENCY USE AUTHORIZATION FOR GOHIBIC (FDA) | https://www.fda.gov/media/166824/download
COVID-19 Ventilator Course: Learn or Review Mechanical Ventilation (MedCram) | https://www.medcram.com/courses/COVID19-ventilator-mechanical-ventilation
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MedCram Update 46: https://youtu.be/EFRwnhfWXxo
MedCram Update 47: https://youtu.be/H1LHgyfPPQ8
MedCram Update 132: https://youtu.be/9OZZ6_M4OB0
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