Matt Parker: “Altered Subgenomic RNA Abundance in SARS-CoV-2 B.1.1.7 Infections”

Matt Parker: “Altered Subgenomic RNA Abundance in SARS-CoV-2 B.1.1.7 Infections”

This week’s speaker is Mattew Parker, a clinical bioinformatician at the Sheffield Biomedical Research Centre.

Parker is a clinical bioinformatician at the Sheffield Biomedical Research Centre, where he is working with the Sheffield COVID-19 genomics group sequencing the genomes of SARS-CoV-2 as part of COG-UK. Parker and the Sheffield COVID-19 genomics group are interested in detecting the expression (subgenomic RNA) of the SARS-CoV-2 genome using the vast amount of genomic sequencing data being generated worldwide. Applying a tool they developed, periscope, they have been using this data to detect differences in subgenomic RNA abundance between circulating lineages of SARS-CoV-2.

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